100 Cases in Clinical Pathology Book
CONTENTS
Preface xi
Acknowledgements xiii
Contributors xv
Section 1: CHEMICAL PATHOLOGY, IMMUNOLOGY AND
GENETICS
Case 1: Polyuria and polydipsia 3
Case 2: Traces of blood found on a routine urine dipstick 7
Case 3: Confusion, lethargy and shortness of breath 9
Case 4: A child with facial swelling 11
Case 5: Joint pains and fatigue 13
Case 6: Anxiety, irritability and reduced menstrual frequency 15
Case 7: Screening for prostate cancer? 19
Case 8: A young woman found unconscious in bed 23
Case 9: A middle-aged woman with jaundice 27
Case 10: Drug overdose 31
Case 11: Fatigue, weakness and constipation 33
Case 12: Excessive hair growth and infertility 37
Case 13: Fatigue and irregular periods 41
Case 14: Stiff and painful hands 43
Case 15: Abdominal pain, nausea and vomiting 47
Case 16: Frequent throat and chest infections 51
Case 17: Right-sided flank pain moving to the groin 53
Case 18: A routine ‘health check’ for a 55-year-old man 55
Case 19: Collapse in a patient undergoing chemotherapy 59
Case 20: A 10-day-old baby with ambiguous genitalia 63
Case 21: Fatigue, weakness and weight gain 67
Case 22: Hypertension in a young woman 69
Case 23: Nausea, vomiting, weakness and paraesthesia 71
Case 24: Erectile dysfunction in a young man 73
Case 25: A young man with ‘high cholesterol’ 75
Case 26: Rash after a bone marrow transplant 77
Case 27: A fall on an outstretched hand 79
Case 28: A patient in follow-up after a liver transplant 81
Case 29: A man with poorly controlled blood pressure 85
Case 30: Dizziness on standing upright 89
Case 31: Sudden-onset chest pain in a tall woman 91
Case 32: Concerns about the risk of breast cancer 93
Case 33: Seizure in a neonate 95
Case 34: Flu-like illness after foreign travel 97
Section 2: HISTOPATHOLOGY
Case 35: A young woman with ankle swelling and shortness of breath 103
Case 36: Chest pain and sudden death 105
Case 37: An elderly man with severe back pain 109
Case 38: Increased breathlessness and sudden death 111
Case 39: A worsening cough and haemoptysis 113
Case 40: A young man with shortness of breath and haemoptysis 117
Case 41: Sudden onset weakness and dysphasia 119
Case 42: Numbness, weakness and clumsiness 121
Case 43: Forgetfulness and disorientation 123
Case 44: Coffee-ground vomiting 125
Case 45: Episodic right upper quadrant abdominal pain 129
Case 46: Chronic diarrhoea and flatulence 133
Case 47: A young man with bloody diarrhoea 135
Case 48: Abdominal discomfort and generalized weakness 139
Case 49: Abdominal pain in a publican 143
Case 50: Abdominal distension, loss of appetite and malaise 145
Case 51: Delayed passage of meconium in a newborn 147
Case 52: Back pain and fever in a diabetic 149
Case 53: Urinary problems in an elderly man 153
Case 54: A young man with a testicular lump 155
Case 55: Heavy and painful menstrual bleeding 159
Case 56: Abnormal vaginal bleeding 163
Case 57: A lump in the breast 165
Case 58: Lymph node enlargement in a young man 167
Case 59: An itchy, bleeding mole on the back 171
Section 3: HAEMATOLOGY
Case 60: Shortness of breath and heartburn 175
Case 61: Raised white cell count in an asymptomatic individual 179
Case 62: Worsening fatigue and bleeding gums 183
Case 63: Burning urine and an abnormal clotting screen 187
Case 64: Headaches, blurred vision and itching 189
Case 65: A painful arm and a large spleen 193
Case 66: A rash on the thighs 197
Case 67: Fatigue and weight loss 201
Case 68: Pneumonia with abnormal liver function 205
Case 69: Recurrent epistaxis 211
Case 70: Bruising after a pneumonia 215
Case 71: Headache and a rash 219
Case 72: Shortness of breath and weight loss 223
Case 73: Low platelets in pregnancy 227
Case 74: Anaemia resistant to a blood transfusion 231
Case 75: Asymptomatic anaemia in the elderly 235
Case 76: Back pain and fatigue 241
Case 77: Short of breath and underweight 245
Case 78: A large epigastric mass 249
Case 79: Deterioration after a blood transfusion 253
Section 4: MICROBIOLOGY
Case 80: Leg pain and fevers 259
Case 81: Fever and collapse 263
Case 82: Burning sensation when passing urine 269
Case 83: A bit short of breath 273
Case 84: Unhappy camper 277
Case 85: Diarrhoea in an elderly man 283
Case 86: A painful knee 287
Case 87: A pain in the ear 291
Case 88: A red eye 293
Case 89: Child with a rash 297
Case 90: Pelvic pain 303
Case 91: A painful swollen jaw 305
Case 92: Traveller’s diarrhoea 311
Case 93: Fever in a returning traveller 315
Case 94: A spot of confusion 319
Case 95: Congenital infection 323
Case 96: A chronic cough 327
Case 97: A jaundiced view 331
Case 98: Gram negative bacteraemia 335
Case 99: A groin swelling 339
Case 100: Urethral discharge 343
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